3 Reasons Why Your MTHFR Treatment Isn't Working

MTHFR is a gene mutation that affects methylation and enzyme production. There are different mutations that can occur, and they affect everyone differently. Some people might barely notice any symptoms while others may develop serious long-term complications. While MTHFR can't be cured, it can be managed.

MTHFR gene mutation treatment typically involves dietary and lifestyle changes. However, even if you follow your treatment protocol, you might still be experiencing problems. Here are 3 reasons why your MTHFR treatment might not be working.


1. You're Consuming Folic Acid Rather Than Folate

Folate and folic acid are both forms of Vitamin B9, a vitamin that's essential for making and repairing DNA, tissue and cell growth, and prevents against anemia. While they're both forms of Vitamin B9, they come from two different sources.

Folate, often called methylated folate, is a natural form of the vitamin while folic acid is the synthetic form. Folate is found in foods, but you'll find folic acid added to fortified foods to reduce a deficiency of the vitamin. At Methyl-Life, we offer several methylfolate supplements to prevent a folate deficiency.

Folate and folic acid aren't the same things. In all reality, folic acid can actually be harmful. Folic acid can actually build up and clog your folate receptors. Even if you take a methylated folate supplement, the folic acid can interfere with the ability of those receptors to use that supplement properly.

2. You're Not Treating the Issue Caused by the Gene Mutation

MTHFR can cause a number of different complications, including digestive issues, heart issues, and mental health issues. Those with the MTHFR gene mutation are prone to leaky gut. Healing your gut health is crucial for improving methylation in your body and improving your overall health. This includes doing things such as reducing your intake of inflammatory foods, eating healthy fats, consuming fermented foods to promote a healthy microbiome in your gut, and eating other foods that are gut-friendly.

As you age, your homocysteine levels are more likely to rise. A high level of homocysteine is linked to a folate deficiency (as well as low levels of Vitamins B6 and B12) and can increase your risk of developing heart disease. For this reason, it's important to keep your heart healthy during the course your MTHFR gene mutation treatment. It's recommended that you exercise regularly, eat a healthy, well-balanced diet, and consider supplements to improve cholesterol, blood pressure, and your blood flow in general.

MTHFR gene mutations are linked to higher instances of mental health disorders. Stress and anxiety can make the symptoms worse. Recommendations for improving mental health include supplementing with omega-3 fatty acids, exercise regularly, practice stress relief, and avoid alcohol and recreational drugs.

3. Other Medications are Interfering

Certain types of medication can actually interfere with folate levels and methylation. This can cause potentially low levels of folate in your body to drop lower. It's important that you discuss your medications with your physician.

Common medications that can interfere with MTHFR gene mutation treatment include birth control pills, sulfa-drugs, antacids, NSAID pain relievers, anti-depressants, nitrous oxide, and Metformin. Make sure to discuss your MTHFR diagnosis with your physician and make sure that you receive the necessary medications that won't interfere with your treatment.

There's a wide range of methylfolate supplements that can help you to manage MTHFR. Knowing where to start can be a bit overwhelming, to say the least. While we always recommend speaking with your doctor to determine your nutrient needs when it comes to your MTHFR gene mutation treatment, we strive to provide you with plenty of helpful resources.

We offer a wide variety of products to help you manage MTHFR and improve your quality of life. For more information, and to get started on a path to a healthier you, contact Methyl-Life today!

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